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The regression also revealed a significant association betwe
2020-06-04

The regression also revealed a significant association between admission selectivity (SELECT) and exam pass rate (PASS%) (p Adenine sulfate serve as an indicator of a student’s ability to learn and their aptitude for academic success. These same qualities likely enable more selective schools to desi
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br Methodology The following subsections describe
2020-06-04

Methodology The following subsections describe the steps of the Systematic Literature Review (SLR) process we followed [9]. Results In our review of the literature, we used the definitions provided by the IEEE Standard Computer Dictionary [15] to categorize the claims about the effectiveness
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It is generally thought that the nature
2020-06-04

It is generally thought that the nature of a memorial and the meaning attributed to it STA-21 by a tourist determines, at least in part, the behaviour that is socially appropriate (Mayo, 1988). Duncan (1995) argues however, that certain places are structured in such a way that they facilitate ritual
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The ubiquitin proteasome system Ub P is the main
2020-06-04

The ubiquitin–proteasome system (Ub–P) is the main cellular machinery for protein turnover in eukaryotic cells (Glickman and Ciechanover, 2002). Degradation by Ub–P involves two steps. Target proteins are selectively, specifically, and covalently attached to ubiquitin (Ub) chains, followed by Ub-tag
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Another example of negative regulation
2020-06-04

Another example of negative regulation is the inhibition of the yeast endosome-associated DUB Doa4 by Rfu1 (free ubiquitin chains 1). In a yeast genetics screen, deletion of Rfu1 was serendipitously found to alter global ubiquitin levels [69]. DUBs can regulate these levels by liberating conjugated
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Main Text Post translational modifications by ubiquitin
2020-06-04

Main Text Post-translational modifications by ubiquitin (Ub) and ubiquitin-like proteins (Ubl) regulate a diverse array of cellular and physiological processes including protein degradation, localization, and activation. While ubiquitination has primary responsibility for targeting substrates for p
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The IV chains of mature GBM are built exclusively
2020-06-03

The α3/α4/α5(IV)-chains of mature GBM are built exclusively by podocytes (not by endothelial cells) (Abrahamson et al., 2009), placing the podocytes into the focus of GBM-diseases such as Alport syndrome. Alport syndrome (AS) is caused by mutations in the COL4A3, 4 or 5 genes coding for the α3/α4/α5
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To better understand Wolbachia s dependence
2020-06-03

To better understand Wolbachia’s dependence on these enzymes, RNAi experiments targeting these transcripts will be required to examine the consequences of their down-regulation on Wolbachia in the different tissues of the parasite. Initial studies have shown that decreases in Bm-cpl-3 and Bm-cpl-6 t
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amiodarone hcl The changes in the chemokine receptors CCR an
2020-06-03

The changes in the chemokine receptors CCR-5 and CXCR-4 in women and men with PTSD are completely different. In the group of women with PTSD alone the level of this amiodarone hcl increased six times, whereas, in women with APD and PTSD, the level of the receptor CCR-5 was eight times higher than i
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br Roles for intracellular chloride channels br Specific
2020-06-03

Roles for intracellular chloride channels Specific chloride channel proteins in intracellular membranes Concluding remarks Introduction The sulfonylurea derivative glybenclamide (GLYB) is used as oral hypoglycemic agent to treat non-insulin dependent diabetes mellitus [1], [2]. The antid
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The CLC proteins in Arabidopsis have
2020-06-03

The CLC proteins in Arabidopsis have been studied in some detail, and a total of seven genes (named AtCLCa-AtCLCg) have been identified (Lv et al., 2009). It is interesting that AtCLCa-AtCLCd and AtCLCg define a distinct phylogenetic branch that is closely related to eukaryotic CLCs, while the other
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Epitope analyses of AT AA and ET AA indicate that
2020-06-03

Epitope analyses of AT1-AA and ET-AA indicate that the sto products of both autoantibodies are located at the second extracelluar loop of both receptors. The specific epitopes for both autoantibodies are similar to what was reported previously in a cohort of patients from Brazil [6] and for AT1-AA
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The estrogenic activity of steroids with a C methyl
2020-06-03

The estrogenic activity of steroids with a C19 methyl group may provide a selective advantage in estrogen physiology that is not provided by E2. In this regard, 5α-androstanediol has been proposed to be a second physiological estrogen in fetal mouse Z-WEHD-FMK receptor based on the timing of ERβ sy
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Here although tibolone reduced the expression of inflammator
2020-06-03

Here, although tibolone reduced the expression of inflammatory genes such as IL6, IL1β, TLR4 and MIR155-3p, in the presence of PA stimulation, it increased the expression of TNF gene. It should be noted that TNF has pleiotropic effects in the CNS, therefore its increased expression does not always i
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Introduction Primitive neuroectodermal tumors PNETs are mali
2020-06-03

Introduction Primitive neuroectodermal tumors (PNETs) are malignant, small round cell tumors of neural crest origin which typically arises from bone or soft tissue in the trunk/axial skeleton/paraspinal regions in adolescents and young adults and comprises of 50% cases with local recurrence and met
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